Registration Dossier
Registration Dossier
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EC number: 433-460-1 | CAS number: 210880-92-5
Endpoint summary
Administrative data
Description of key information
Additional information
The substance (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine was shown to be hydrolytically stable at 50 °C and pH 4, 5 and 7 but slowly degraded at pH 9. By using different temperatures (50°C, 62°C and 74°C), it was possible to show that the half-life of the test substance at pH 9 and 20°C would be ca 3.8 years. Transformation products were produced at pH 9 from the test substance, but they were only produced at artificially high temperatures. At the temperature of environmental concern (20°C), these products would not be expected to be produced in significant amounts. Thus, hydrolysis is not a route of degradation under environmental conditions (pH 4-9, 20°C).
However, sunlight can be considered as the major abiotic degradation pathway in air, in the aqueous environment and in soil. In air the photolytical half-life of the substance was estimated to 1.5 hours, based on modelling. In water the photolytical half-life was found to range from 25.0 to 27.8 hours in natural water and to be 3.3 hours in sterile aqueous buffer solution at pH 7. In soil a half-life of 8.2 days in artificial sunlight was recorded for the target substance.
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