Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor
PNEC marine water (intermittent releases):
0 mg/L

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
10 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.002 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.03 mg/kg soil dw
Assessment factor:
10
Extrapolation method:
assessment factor

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Classification related key information

Biodegradation in water: Not readily biodegradable

Log Kow:≤3

Acute toxicity:

- to Fish: LC50(96h) > 100 mg/L (nominal) for Cyprinodon variegatus (EPA OPPTS 850.1075)

- to aquatic invertebrates: EC50(48h) = 0.029 mg/L (nominal) for Chironomus riparius (EPA OPPTS 850.1790)

- to algae: ECr50 (96h) = 37.8 mg/L (nominal) for Skeletonema costatum (OECD 201)

Chronic toxicity:

- to Fish: NOEC (33 d) was ≥ 20 mg/L (mean meas.) for Pimephales promelas (EPA OPPTS 850.1400)

- to aquatic invertebrates: EC10 (28d) = 0.0004 mg/L (mean meas.) for Chironomus riparius (BBA-method)

- to Algae: NOEC (96h) = 6.4 mg/L (nominal) for Skeletonema costatum (OECD 201)

Classification justification according to CLP

According to the data listed above Clothianidin is not rapidly biodegradable and has a low potential to bioaccumulate (log Kow: ≤ 3). The most sensitive acute effect was obtained for Chironomus ripariuswith an EC50(48 h) of 0.029 mg/L. The most sensitive chronic effect was the reported EC10(28 d) of 0.0004 mg/L in a chronic toxicity study on Chironomus riparius. Based on the available data substance is need to be classified and labelled as environmentally hazardous category Acute 1 and Chronic 1. This in line with harmonised classification of Clothianidin on Annex VI to CLP_ATP01. The harmonised classification and labelling is Aquatic Acute 1 and Aquatic Chronic 1 according to Annex VI to CLP.

 

M-factor for acute: 10

M-factor for chronic toxicity: 100