Registration Dossier
Registration Dossier
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EC number: 433-460-1 | CAS number: 210880-92-5
Endpoint summary
Administrative data
Description of key information
Additional information
The main abiotic pathway for degradation of the target compound (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine is photodegradation in soil with a half-life of 8.2 days, while hydrolysis is no relevant degradation process of the test substance and (at 12 °C DT50 = > 1 year at pH 4, pH 7 and pH 9).
A study on the ready biodegradability of the substance is not available. Biodegradation of the substance was investigated in a simulation study with different water/sediment systems. The substance was rapidly transferred from water to sediment, half-lives of the target compound at 20 °C ranged from 48 – 65 days (102 – 138 days, recalculated to 12 °C) in the water/sediment systems. After an incubation period of 100 days 14CO2 accounted for <5% of the initially applied radioactivity.
In a simulation study on the biodegradation of the test compound in water the DT50 was determined to be > 1 year at 20.5 °C.
Three different simulation studies investigating the degradation in a total of ten soil types (sand, loamy sand, sandy loam, loam, silt loam and clay loam). The DT50 values in different soils ranged from 9.7 to 1328 days (32.9 - 2819 days, recalculated to 12 °C) with 9.4 – 29.3% mineralisation after 120 to 379 days.
However, the log Koc value of 2.54 indicates a low potential of the substance for adsorption to soil and sediment particles.
The substance is soluble in water (WS: 0.327 g/L at 20 °C, OECD 105); volatilization from the water phase is not indicated by the Henry's Law Constant of 2.9 Pa m³/mol. Because of the low log Kow (<= 3) the substance is expected to exhibit a low potential for bioaccumulation.
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