Registration Dossier
Registration Dossier
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EC number: 200-309-2 | CAS number: 57-06-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Larvicidal Activity of Myrtaceae Essential Oils and Their Components Against Aedes aegypti, Acute Toxicity on Daphnia Magna and Aqueous Residue
- Author:
- Hye-Mi Park, Junheon Kim, Kyu-Sik Chang, Byung-SeokKim, Yu-Jung Yang, Gil-Hah Kim, Sang-Chul Shin and Il-Kwon Park
- Year:
- 2 011
- Bibliographic source:
- Park et al., Larvicidal Activity of Myrtaceae Plant Essential Oils, J. Med. Entomol. 48(2): 405-410 (2011)
Materials and methods
- Principles of method if other than guideline:
- Acute Toxicity on Daphnia magna were conducted according to standard methods of the United States Environmental Protection Agency (USEPA 2002).
- GLP compliance:
- not specified
- Remarks:
- GLP compliance not specified
Test material
- Reference substance name:
- Allyl isothiocyanate
- EC Number:
- 200-309-2
- EC Name:
- Allyl isothiocyanate
- Cas Number:
- 57-06-7
- Molecular formula:
- C4H5NS
- IUPAC Name:
- 3-isothiocyanatoprop-1-ene
- Test material form:
- liquid
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- not specified
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- Temperature maintained at 20 +/- 1 C.
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.73 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Among the constituents tested, allyl isothiocyanate was the most toxic within a 50 % effective concentration value of 0.735 mg/L.
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