Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: short-term
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1953
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Dodecylamine and other agents active against Ascaris lumbricoides and their toxicity in mammals
Author:
Hamilton H. Anderson and George K. Hurwitz
Year:
1953
Bibliographic source:
Arch. exper. Path. u. Pharmakol., Bd. 219, S. 119-129 (1953)

Materials and methods

Principles of method if other than guideline:
Test items were tested on Ascaris lumbricoides of swine. The chemical to be tested was diluted approximately 1:1000 in 0,9% NaCl solution.
(modification of the LAMSON and BROW~ method, 1936)

Test material

Constituent 1
Chemical structure
Reference substance name:
Allyl isothiocyanate
EC Number:
200-309-2
EC Name:
Allyl isothiocyanate
Cas Number:
57-06-7
Molecular formula:
C4H5NS
IUPAC Name:
3-isothiocyanatoprop-1-ene
Test material form:
liquid

Test substrate

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Ascaris lumbricoides
Animal group:
nematods

Study design

Study type:
laboratory study
Substrate type:
not specified
Total exposure duration:
1 h

Test conditions

Test temperature:
37 C

Results and discussion

Effect concentrations
Duration:
1 h
Dose descriptor:
LC100
Effect conc.:
1 other: g/L of a 0.9% NaCl solution
Nominal / measured:
nominal
Details on results:
Allyl isothiocyanate killed all worms in 30 minutes.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
Allyl isothiocyanate killed all worms in 30 minutes.