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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Bioconcentration factor (24-336 hr exposure) for carp exposed to 14.7 and 0.67 µg l-1 under continuous flow-through conditions, 0.8 and 2.2, respectively. Whole-body excretion rate constant 0.21 hr-1.This low value of BCF of 3-chloroaniline indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000.

Key value for chemical safety assessment

BCF (aquatic species):
0.8 L/kg ww

Additional information

Based on weight of evidence approach no. of studies were reviewed for bioaccumulation from reliable sources having Klimish rating 2 and 4 for CAS No.:108-42-9

The summary of the results are presented below:

Sr. No

Endpoint name

Value

Interpretation of result

Conclusion

Sources

1.

BCF

0.8 – 2.2 L/kg

Non bioaccumulative

Bioconcentration factor (24-336 hr exposure) for carp exposed to 14.7 and 0.67 µg l-1 under continuous flow-through conditions, 0.8 and 2.2, respectively. Whole-body excretion rate constant 0.21 hr-1.This low value of BCF of 3-chloroaniline indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000.

Experimental data for CAS : 108-42-9

2.

BCF

11.5

Non bioaccumulative

The Bioconcentration factor (BCF) for zebrafish exposed to 3-chloroaniline (0.0002 mg/L) under static conditions was reported as 11.5 suggesting that 3-chloroaniline is non bioaccumulative in nature as the BCF factor is less than the bio-concentration threshold of 2000.

Experimental data for CAS : 108-42-9

3.

BCF

8.1

Non bioaccumulative

The estimated bioconcentration factor (BCF) for 3-Chloroaniline is 8.1,which does not exceeds the bioconcentration threshold of 2000.Thus, it is concluded that 3-Chloroaniline is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria. 

Predicted data for CAS : 108-42-9

4.

BCF

8.08

Non bioaccumulative

The estimated bioconcentration factor (BCF) for 3-Chloroaniline is 8.08,which does not exceeds the bioconcentration threshold of 2000.Thus, it is concluded that 3-Chloroaniline is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria. 

Predicted data for CAS : 108-42-9

 

Based on the studies summarized in the above table for target substance 3-Chloroaniline,the bioconcentration value (BCF) was found to vary between 0.8 to 11.5. This low value of BCF of 3-Chloroaniline indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000.