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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The no observable effect concentration (NOEC) value of 3-chloroaniline in aquatic invertebrate (Daphnia magna) in a 21 days study on the basis of reproduction effect was found to be 0.013 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.013 mg/L

Additional information

No. of studies were reviewed for Long-term toxicity to aquatic invertebrates from reliable sources having Klimisch rating 2 and 4.

The summary of the results are presented below  




Effect values

Basis for effects






0.013 mg/L


21 days

Daphnia magna

Experimental data from Water Res for CAS : 108-42-9



0.26 mg/L


21 days

Daphnia magna

Experimental data for CAS : 108-42-9


Based on the studies summarized in the above table for the target substance 3-chloroaniline,the endpoint value was found to vary between the no observed effect concentration (NOEC) = 0.013 mg/L and lethal concentration (LC50) = 0.26 mg/L in a 21 days study on the basis of mortality and reproduction effect.