Registration Dossier
Registration Dossier
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EC number: 203-581-0 | CAS number: 108-42-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Remarks:
- in vivo
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
- Principles of method if other than guideline:
- The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
- GLP compliance:
- not specified
- Justification for non-LLNA method:
- not specified
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
- Reading:
- other: not specified
- Group:
- test chemical
- Remarks on result:
- positive indication of skin sensitisation
- Interpretation of results:
- sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
- Executive summary:
The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
Migrated from Short description of key information:
The test substance 3-chloroaniline was found to be a skin sensitizer.
Justification for selection of skin sensitisation endpoint:
The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The test substance 3-chloroaniline is considered as sensitising for the purpose of classification.
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