Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-581-0 | CAS number: 108-42-9
Endpoint summary
Administrative data
Description of key information
Additional information
Based on weight of evidence approach no. of studies were reviewed for bioaccumulation from reliable sources having Klimish rating 2 and 4 for CAS No.:108-42-9
The summary of the results are presented below:
Sr. No |
Endpoint name |
Value |
Interpretation of result |
Conclusion |
Sources |
1. |
BCF |
0.8 – 2.2 L/kg |
Non bioaccumulative |
Bioconcentration factor (24-336 hr exposure) for carp exposed to 14.7 and 0.67 µg l-1 under continuous flow-through conditions, 0.8 and 2.2, respectively. Whole-body excretion rate constant 0.21 hr-1.This low value of BCF of 3-chloroaniline indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000. |
Experimental data for CAS : 108-42-9 |
2. |
BCF |
11.5 |
Non bioaccumulative |
The Bioconcentration factor (BCF) for zebrafish exposed to 3-chloroaniline (0.0002 mg/L) under static conditions was reported as 11.5 suggesting that 3-chloroaniline is non bioaccumulative in nature as the BCF factor is less than the bio-concentration threshold of 2000. |
Experimental data for CAS : 108-42-9 |
3. |
BCF |
8.1 |
Non bioaccumulative |
The estimated bioconcentration factor (BCF) for 3-Chloroaniline is 8.1,which does not exceeds the bioconcentration threshold of 2000.Thus, it is concluded that 3-Chloroaniline is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria. |
Predicted data for CAS : 108-42-9 |
4. |
BCF |
8.08 |
Non bioaccumulative |
The estimated bioconcentration factor (BCF) for 3-Chloroaniline is 8.08,which does not exceeds the bioconcentration threshold of 2000.Thus, it is concluded that 3-Chloroaniline is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria. |
Predicted data for CAS : 108-42-9 |
Based on the studies summarized in the above table for target substance 3-Chloroaniline,the bioconcentration value (BCF) was found to vary between 0.8 to 11.5. This low value of BCF of 3-Chloroaniline indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
