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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to terrestrial arthropods

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Administrative data

Link to relevant study record(s)

Description of key information

The lethal dose (LD50) of 3-chloroaniline in terrestrial arthropods [Apis mellifera] in a short term study of 48 hrs. on the basis of mortality effect was estimated to be 82.625 µg per animal.

Key value for chemical safety assessment

Short-term EC50 or LC50 for soil dwelling arthropods:

Additional information

No. of studies were reviewed for toxicity to terrestrial arthropods from reliable sources having Klimisch rating 2 and 4.

The summary of the results are presented below  




Effect values

Basis for effects






82.625 µg per animal


48 hrs

Apis mellifera

Predicted data from QSAR for CAS :108-42-9



10 -30 mg/kg soil dw


28 days

Folsomia candida

Experimental data from J. Soils Sediments for RA CAS : 95-76-1


Based on the studies summarized in the above table for the target substance 3-chloroaniline and the read across substance 3,4-dichloroaniline in terrestrial arthropods (Apis mellifera and Folsomia candida),the endpoint value was found to vary between the lethal dose (LD50) = 82.625 µg per animal and effective concentration (EC50) = 10 -30 mg/kg soil dw in a 48 hrs study to 28 days study on the basis of mortality and reproduction effect.