Registration Dossier
Registration Dossier
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EC number: 203-629-0 | CAS number: 108-91-8
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- other: occupational poisoning
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: limited documentation
Data source
Reference
- Reference Type:
- publication
- Title:
- Cyclohexylamine, p-chlornitrobenzene, 2-Aminopyridine: Toxic effects in industrial use
- Author:
- Watrous RM, Schulz HN
- Year:
- 1 950
- Bibliographic source:
- Ind. Med. Surg. 19, 317-320
Materials and methods
- Study type:
- study with volunteers
- Endpoint addressed:
- acute toxicity: inhalation
- Principles of method if other than guideline:
- clinical case of exposure to cyclohexylamine
- GLP compliance:
- no
Test material
- Reference substance name:
- Cyclohexylamine
- EC Number:
- 203-629-0
- EC Name:
- Cyclohexylamine
- Cas Number:
- 108-91-8
- Molecular formula:
- C6H13N
- IUPAC Name:
- cyclohexanamine
Constituent 1
Method
- Subjects:
- Workplace incidental poisoning with an unknown concentration of cyclohexylamine; subsequent workplace measurement indicated no symtomes at 16-41 mg/m3 (no further details).
- Route of exposure:
- inhalation
- Reason of exposure:
- unintentional, occupational
- Exposure assessment:
- not specified
Results and discussion
- Clinical signs:
- strong fishy smell, sensation of light headedness, felt great anxiety, hours later felt faint, became nauseatic and vomited, no appetite, restlessness and apprehension, burning in his throat,rapid heart beat
Any other information on results incl. tables
the two patients recovered during the next days
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
