Registration Dossier
Registration Dossier
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EC number: 203-629-0 | CAS number: 108-91-8
Endpoint summary
Administrative data
Description of key information
Additional information
Stability (phototransformation in air):
In the atmosphere, a half-life of 6.95 h and 11.2 h for the neutral and protonated form of cyclohexylamine was estimated, respectively assuming a reaction with photochemically produced hydroxyl radicals. According to the guidance document R.11 (ECHA, 2008, p19), substances characterized by an atmospheric half-life smaller than 2 days does not have the potential for a long range atmospheric transport and thus the deposition in remoted areas.
Biodegradation (in water, screening test):
Cyclohexylamine is readily biodegradable as 92 % of the test item were degraded after 20 days when tested according to EU Method C4 -E.
Bioaccumulation:
The potential of cyclohexylamine to accumulate in aquatic organisms is characterized by a calculated BCF of 2.8 and 3.162 for the neutral and protonated form, respectively assuming only a very low potential for bioaccumulation.
Transport and Distribution (Henry's Law Constant)
Cyclohexylamine is characterized by a measured Henry's Law Constant of 0.42 Pa*m³/mol at a temperature of 25 °C.
Based on a dissociation constant of 10.68 (Perrin, 1965), the substance will, under environmental relevant conditions (pH 4 to 9), be present solely in the protonated form. Therefore, the measured HLC reflects the properties of the protonated form rather than the neutral species. According to Thomas, cited in the "Handbook of Chemical property Estimation Methods" (Lyman, 1980), cyclohexylamine volatilizes only slowly from water, whereas the rate is strongly controlled by the slow diffusion through air.
Transport and Distribution (Distribution Modelling)
Under environmental relevant conditions (pH 4 to 9), cyclohexylamine will completely be protonated. Based on Model calculations according to Mackay Level I, the target environmental compartment for the protonated form of cyclohexylamine is water.
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