Registration Dossier
Registration Dossier
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EC number: 203-629-0 | CAS number: 108-91-8
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The potential of cyclohexylamine to accumulate in aquatic organisms is characterized by a calculated BCF of 2.8 and 3.162 for the neutral and protonated form, respectively (Bayer Industry Services, 2006) assuming only a very low potential for bioaccumulation.
Key value for chemical safety assessment
Additional information
Calculated BCF values were used for the hazard assessment of cyclohexylamine despite the fact, that for ionisable substances measured BCF values are preferred over calculated ones. Bioconcentration factors are used to assess the potential to accumulate in aquatic organisms, mainly in the scope of the PBT assessment. Thus, vertebrate-animal testing can be avoided as no additional information is gained through that test. The substance is neither classified as persistent, nor as toxic to aquatic organisms, a measured BCF value would not change the outcome of the PBT assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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