Registration Dossier
Registration Dossier
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EC number: 701-257-8 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No data on purity of test sample, non-GLP
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
Materials and methods
- Principles of method if other than guideline:
- Acute oral toxicity in male rats
- GLP compliance:
- not specified
- Test type:
- other: Acute oral toxicity in male rats
- Limit test:
- no
Test material
- Reference substance name:
- C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
- EC Number:
- 701-257-8
- IUPAC Name:
- C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
- Details on test material:
- no data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- other: none
- Doses:
- 5.0; 15.0 ml/kg bw.
- No. of animals per sex per dose:
- 10 male rats/dose
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 15 mL/kg bw
Any other information on results incl. tables
| Dose (ml/kg bw) | Timepoint of death | Toxicological result (No.of mortalities/ Animals with Symptoms/ No.of animals) |
5.0 |
- |
0/0/10 |
15.0 |
- |
0/10/10 |
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Executive summary:
The acute oral toxicity of Mesamoll was tested in male Wistar rats treated via gavage with the doses: 5.0 and 15.0 ml/kg bw. The observation period was 14 days. No mortalities could be observed. Signs of intoxication were observed in the 15.0 ml/kg bw dose group (apathy, ruffled fur and diarrhea). The LD 50 was higher than 15 ml/kg bw (corresponds to 15.9 g/kg).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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