Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: No OECD guideline or GLP defined; no data on purity of test sample
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1975

Materials and methods

Principles of method if other than guideline:
other: acute i.p. toxicity study in male rats
GLP compliance:
not specified
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
EC Number:
701-257-8
IUPAC Name:
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters
Test material form:
liquid

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
unchanged (no vehicle)
Doses:
5.0 ml/kg
No. of animals per sex per dose:
10 male rats/dose
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
> 5 275 mg/kg bw

Any other information on results incl. tables

 Dose (ml/kg bw)  Timepoint of death  Toxicological result (Nr.of mortalities/Animals with symptoms/No.of animals)
 5.0  -  0/0/10

Applicant's summary and conclusion

Executive summary:

The acute intraperitoneal toxicity of Mesamoll was tested in male Wistar rats. The dose tested was 5.0 ml/kg bw.

No mortalities and no signs of intoxication could be observed.

Regarding the density of Mesamoll (1.055 g/cm³ at 20 °C) the LD 50 was higher than 5275 mg/kg bw.