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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1969
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Relevance of test system not clear

Data source

Reference
Reference Type:
publication
Title:
Effects of photosynthesis inhibiting acylanilides on the activity of mammal mitochondria
Author:
Inoue, Y., Ishizuka, K., Mitsui, S.
Year:
1969
Bibliographic source:
Agr. Biol. Chem. 33, 1798-1801 (1969)

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
no
Remarks:
pre-dates GLP

Test material

Constituent 1
Chemical structure
Reference substance name:
2,4,5-trichloroaniline
EC Number:
211-254-9
EC Name:
2,4,5-trichloroaniline
Cas Number:
636-30-6
Molecular formula:
C6H4Cl3N
IUPAC Name:
2,4,5-trichloroaniline
Constituent 2
Reference substance name:
2,4,5-trichloraniline
IUPAC Name:
2,4,5-trichloraniline

Results and discussion

Any other information on results incl. tables

Result: A concentration dependent stimulative effect of the
test substance on the oxygen consumption and lost of the
respiratory control ability of the mitochondria was
interpreted as a high potential for uncoupling of oxidative
phosphorylation.

Applicant's summary and conclusion