Registration Dossier
Registration Dossier
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EC number: 459-270-7 | CAS number: 2568-33-4 MBD
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption, other
- Remarks:
- Estimation of the Adsorption Coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 Jul 2005 – 25 Oct 2005
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 52834
- Expiration date of the lot/batch: 8 Nov 2004
- Purity: 99.08%
- Storage condition: Room temperature in the dark - Radiolabelling:
- not specified
- Test temperature:
- 25°C
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: Hewlett Packard 1050 Liquid Chromatograph
- Column: Hyperclone 5µ CN (25 cm x 4.6 mm ID)
- Mobile Phase Composition: Methanol:water (55:45 v/v)
- Flow rate: 1.0 mL/min
- Injection volume 10 µL
- Detector: Philips PU4026 Refractive Index Detector - Analytical monitoring:
- not specified
- Key result
- Type:
- Koc
- Value:
- < 1.3 dimensionless
- Temp.:
- 25 °C
- Details on results (HPLC method):
- A limited test only was performed due to the anticipated low log10Koc value. A solution of test item (50g/L in methanol) was prepared and chromatographed alongside a sample of reference substance acetanilide (1g/L in methanol), which has a known log10Koc value of 1.25
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Under the conditions of the test, test item was found to elute before the reference substance acetanilide.
The test item was found to have a log10Koc value of less than 1.3
Reference
Description of key information
Under the conditions of the test, test item was found to elute before the reference substance acetanilide.
The test item was found to have a log10Koc value of less than 1.3.
Key value for chemical safety assessment
- Koc at 20 °C:
- 20
Additional information
[LogKoc: 1.3]
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