Registration Dossier
Registration Dossier
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EC number: 210-519-6 | CAS number: 617-52-7
Endpoint summary
Administrative data
Description of key information
Additional information
- ECB European Chemicals Bureau (2003) Technical Guidance Document in support of Commission Directive 93/67/EEC on Risk Assessment for new notified substances, Commission Regulation (EC) No 1488/94 on Risk Assessment for existing substances and Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market. Parts I to IV. Self-published.
- ECHA R.7c: European Chemicals Agency (2014). Guidance on information requirements and chemical safety assessment. Chapter R.7c: Endpoint specific guidance. Version 2.0., Document Reference ECHA-14-G-06-EN, ISBN 978-92-9244-762-5. Self-published, Helsinki, Finland, in November. 259 p.
Equilibrium Partitioning Method (EPM)
Due to its ready biodegradability the submission item belongs to the lowest “Soil hazard category 1” (according to ECHA R.7c, 2014, Table R.7.11-2, p 145) and thus the straight forward application of the EPM according to the TGD (ECB 2003, part II, p 112) is supported to assess the hazard and to derive the Predicted No Effect Concentrations (PNECs) for soils.
Effect data exist from non-standard studies and indicate the lower L(E)C50 of 52.7 mg/kg soil dw for terrestrial plant effects, while the nematode LC50 is reported to be 435 mg/kg soil dw.
The application of an assessment factor of 1000 according to ECHA R.10 (2008, Table R.10-10, p 41) to the lowest known L(E)C50 from terrestrial organisms, i.e. 52.7 mg/kg soil dw for plants would result in a 10 times higher PNEC than the one derived by EPM, which was therefore preferred over the actual non-standard test data for precautionary reasons.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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