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Administrative data

Link to relevant study record(s)

Description of key information

No inherent capacity to biomagnify in terrestrial food webs

Key value for chemical safety assessment

Additional information

No experimental data on bioaccumulation in terrestrial organisms are available. Due to the low lipophilicity as expressed by a Log Kow < 2 such fast urinary excretion is assumed that slow elimination by exhalation in air-respiring species will be overcompensated (Gobas et al. 2009, p 634). Nonetheless Koa is the second relevant figure in the context of terrestrial bioconcentration in terrestrial food chains and is therefore derived below.

n-Octanol/Air Partition Coefficient (Koa)

As Kow is by definition (concentration of solute in n-octanol)/(concentration of solute in water), the n-octanol-air partition coefficient Koa = (concentration of solute in n-octanol)/(concentration of solute in air) can be directly derived when Kow and Kaw are known (White 2009, equation 3, p 7):

Koa = Kow/Kaw

As Kow was determined to be 7.2 (Brekelmans 2010) and the Kaw is derived in the chapter on Henry's Law constant to be 7.487, the n-octanol/air partition coefficient is calculated to:

Koa = 7.2 / (7.487 · 10^-6) = 961'666

The calculation based on measured n-octanol/water partition coefficient, vapour pressure and water solubility resulted thus in (rounded):

Koa = 1.0 · 10^6, Log Koa = 6.0

This value indicates according to Gobas et al. (2009, p 634) slow elimination by exhalation as Log Koa is > 5.


In result absence of capacity to biomagnify in terrestrial food webs is concluded irrespective of slow elimination by exhalation assumed because of the Log Koa of > 5. Fast urinary excretion due to low lipophilicity and additionally the rapid and ready biodegradability, which suggest a high rate of metabolic transformation, is expected to prevent any terrestrial bioaccumulation.

  • Gobas FAPC, de Wolf W, Burkhard LP, Verbruggen E, Plotzke K (2009). Revisiting Bioaccumulation Criteria for POPs and PBT Assessments. DOI 10.1897/IEAM_2008-089.1 PMID 19552497 Online ISSN 1551-3793 Integrated Environmental Assessment and Management 5(4):624–37.
  • White K (2009). Guidance for Reporting on the Environmental Fate and Transport of the Stressors of Concern in Problem Formulations for Registration Review, Registration Review Risk Assessments, Listed Species Litigation Assessments, New Chemical Risk Assessments, and Other Relevant Risk Assessment. U.S. EPA, Office of Pesticide Programs, Environmental Fate and Effects Division, published 14 December 14. 19 p.URL