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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Certain details lacking, but considered suitable to confirm similar results as would be expected for this substances
Study provided on similar substance to help build up a weight of evidence demonstrating potential for read-across between the xanthates

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
CCOHS, Registry of Toxic Effects of Chemical Substances, updated July 2010,
Author:
CCOHS, Registry of Toxic Effects of Chemical Substances
Year:
2010
Bibliographic source:
www.ccohs.ca
Reference Type:
secondary source
Title:
No information
Author:
Izmerov, N.F.et all
Year:
1982
Bibliographic source:
Moscow, Centr of International Projects, GKNT, vol.102

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 403 (Acute Inhalation Toxicity)
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Potassium O-butyl dithiocarbonate
EC Number:
212-808-2
EC Name:
Potassium O-butyl dithiocarbonate
Cas Number:
871-58-9
IUPAC Name:
potassium O-butyl dithiocarbonate
Constituent 2
Reference substance name:
Potassium n-butyl xanthate
IUPAC Name:
Potassium n-butyl xanthate
Test material form:
not specified

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Duration of exposure:
2 h
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
7 690 mg/m³ air
Clinical signs:
other:

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Executive summary:

Certain details lacking, but considered suitable to confirm similar results as would be expected for this substances


Study provided on similar substance to help build up a weight of evidence demonstrating potential for read-across between the xanthates