Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dermal absorption, other
Remarks:
Calculation
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Justification for type of information:
This calculation has been migrated from earlier versions of IUCLID, but has been retained as providing some useful indications of possible migration through the skin of the parent substance
In reality, any dermal absorption will relate to carbon disulphide and the respective alcohols

Data source

Reference
Reference Type:
other: model
Title:
Unnamed
Year:
2011

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Estimation Programs Interface Suite for Microsoft Windows, Dermwin v 2.01

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium O-isobutyl dithiocarbonate
EC Number:
246-805-2
EC Name:
Sodium O-isobutyl dithiocarbonate
Cas Number:
25306-75-6
Molecular formula:
C5H10OS2.Na
IUPAC Name:
sodium [(2-methylpropoxy)methanethioyl]sulfanide

Results and discussion

Percutaneous absorption
Remarks on result:
other: KP cm/h predicted=2.22 ×10E-5

Applicant's summary and conclusion