Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 268-626-9 | CAS number: 68131-73-7
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The chemical safety assessment according to Annex I of Regulation (EC) 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no further long-term toxicity test to fish is proposed. Acute toxicity data are available for all three relevant trophic levels i.e. fish, aquatic invertebrates and algae. The most sensitive test organism was algae. The determined EC50(72 h) was 0.5 mg/L. The reported acute effect concentration for Daphnia magna was 2.2 mg/L (EC50(48 h)). Detrimental effects on fish were not observed in the available acute toxicity study on Poecilia reticulata. Thus fish are not the most sensitive species. Therefore long-term toxicity testing with fish was omitted. Chronic toxicity data are available for aquatic invertebrates and algae. A read across study on the long-term toxicity of the source substance Triethylenetetramine linear, cyclic and branched (TETA; CAS 90640-67-8) to aquatic invertebrates determined an EC50 of 10 mg/L (nominal) based on the reproduction rate after 21 days of exposure. The EC10 of 1.9 mg/L was determined via interpolation. In the available study on the toxicity of the target substance to aquatic algae a NOEC (72 h) of 0.16 mg/L for algal growth and biomass respectively was determined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
