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Toxicological information

Dermal absorption

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Administrative data

Endpoint:
dermal absorption in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1951
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: The study was performed pre-GLP and pre-guideline. Limited reporting. No information on the composition or purity of the test substance.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1953
Report date:
1953

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Amines, polyethylenepoly-, triethylenetetramine fraction
EC Number:
292-588-2
EC Name:
Amines, polyethylenepoly-, triethylenetetramine fraction
Cas Number:
90640-67-8
Molecular formula:
C6H18N4, C8H20N4
IUPAC Name:
Amines, polyethylenepoly-, triethylenetetramine fraction
Test material form:
liquid
Radiolabelling:
no

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
no data
No. of animals per group:
no data

Results and discussion

Conversion factor human vs. animal skin:
no data

Any other information on results incl. tables

The material was not absorbed in acutely toxic amounts.

Applicant's summary and conclusion

Conclusions:
The material was not absorbed in acutely toxic amounts.
Executive summary:

Through rabbit skin the material was not absorbed in acutely toxic amounts. No further information.