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EC number: 268-626-9 | CAS number: 68131-73-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Experimental data on the toxicity of Amines, polyethylenepoly (PEPA; CAS 68131-73-7) to terrestrial organisms are available for earthworms (soil macroorganisms). Earthworms are responsible for the breakdown and incorporation of organic matter into the soil and thus will be mainly exposed via the uptake of soil material and via contact with soil pore water. The main exposure route of the animals is dependent on the bioavailability and thus the substance properties. The test substance is characterized by a high water solubility (WS >50 g/L), a low vapour pressure (7.65E-4 Pa) and a log Koc >3.5. Thus the substance is expected to be present in soil pore water and adsorb to soil and suspended matter. Furthermore the substance is not readily biodegradable. Thus, in accordance with section R.7.11.5.3. of Chapter R.7c of the ECHA Guidance on information requirements and chemical safety assessment (ECHA, 2017) long-term tests were conducted in order to assess the toxicity of the substance to terrestrial organisms. The toxicity to earthworms was tested according to OECD guideline 222 with Eisenia fetida as test species. During an exposure period of 56 days (in total) the mortality of adult earthworms as well as the reproduction rate were recorded. An effect of the substance on the reproduction rate was not determined. The reported NOEC is 1000 mg/kg soil dw.
Additionally data from a short summary on the toxicity to birds of the read across substance N,N'-bis(2-aminoethyl)ethane-1,2-diamine (CAS 112-24-3) are available. Wild-trapped birds were preconditioned to captivity for 2 to 6 weeks and were usually dosed by gavage with solutions or suspensions of the test chemical in propylene glycol. The LD50 was estimated based on the food consumption measured over a period of 18 hours. A LD50 (18 h) of 100 - 133 mg/kg was calculated.
The available data is deemed sufficient to assess the terrestrial toxicity of the test substance. Further tests on soil organisms are therefore not conducted.
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