Registration Dossier
Registration Dossier
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EC number: 222-023-7 | CAS number: 3320-83-0
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-chlorophenyl isocyanate
- EC Number:
- 222-023-7
- EC Name:
- 2-chlorophenyl isocyanate
- Cas Number:
- 3320-83-0
- Molecular formula:
- C7H4ClNO
- IUPAC Name:
- 1-chloro-2-isocyanatobenzene
- Details on test material:
- purity not specified
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - filtration
- aeration over 7 days
- concentration: 5 mg/L - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 5.2 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- - direct weight
- temperature: 20 +/- 1 °C
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 21 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- degradation 75 % after 14 days
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
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