Registration Dossier
Registration Dossier
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EC number: 222-023-7 | CAS number: 3320-83-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxcity of 2-chloro aniline, being the hydrolysis product of 2-chlorophenyl isocyanate, towards aquatic invertebrates (Daphnia magna) is characterized by a LC50 of 0.13 mg/L during 48 hours (Maas-Diepeveen and van Leeuwen, 1986).
Key value for chemical safety assessment
Additional information
Isocyanates are known to rapidly hydrolyse under the formation of the corresponding amine. Thus, it is not possible to obtain a stable concentration of 2-chlorophenyl isocyanate over the whole test duration due to its rapid hydrolysis and observed effects would be rather caused by the transformation product (2-chloro aniline) than by the original substance itself. Concluding, results obtained through the testing of 2-chloro aniline can be used to assess the risk of 2-chlorophenyl isocyanate towards aquatic organisms as well.
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