Registration Dossier
Registration Dossier
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EC number: 500-345-1 | CAS number: 157627-95-7 1 - 2.5 moles ethoxylated
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96 h LC50 (Danio rerio) = 7.1 mg/L a.i. (nominal, OECD 203)
48 h LC50 (Leuciscus idus) = 4.3 mg/L a.i. (nominal, DIN 38412)
Key value for chemical safety assessment
Additional information
The assessment is based on the data currently available. New studies, based on the category review and the final decisions issued for some of the category substances, which are also relevant for this assessment, are currently being conducted. The hazard assessment with respect to aquatic toxicity will be updated once all ongoing studies have been finalised.
One study investigating the acute toxicity of AES (C16 -18 and C18-unsaturated, 1-2.5 EO) Na (CAS 157627-95-7) to fish is available (Richterich & Mühlberg, 1999). The study was conducted with the golden orfe Leuciscus idus under static conditions according to national German standards (DIN 38412 part 15) and resulted in an EC50 (48h) value of 4.3 mg/L a.i. (nominal). Due to the short test duration of 48 hours the study reflects not the current standard procedure. Furthermore only a short study report is available. Hence an additional read across study was chosen to assess the acute fish toxicity. The read across study was performed according to OECD guideline 203 in compliance with GLP requirements (Scholz, 1994). Under flow-through conditions zebra fish (Danio rerio) were exposed to AES (C12-14, 1-2.5EO) Na (CAS 68891-38-3). After 96 h a LC50 of 7.1 mg a.i./L (nominal) was determined.
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