Registration Dossier
Registration Dossier
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EC number: 500-345-1 | CAS number: 157627-95-7 1 - 2.5 moles ethoxylated
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48h) Daphnia magna = 1.4 mg/L a.i. (nominal, OECD 202)
Key value for chemical safety assessment
Additional information
The assessment is based on the data currently available. New studies, based on the category review and the final decisions issued for some of the category substances, which are also relevant for this assessment, are currently being conducted. The hazard assessment with respect to aquatic toxicity will be updated once all ongoing studies have been finalised.
Since no data on acute aquatic toxic to invertebrates for AES (C16 -18 and C18-unsaturated, 1-2.5 EO) Na (CAS 157627-95-7) are available, a read-across approach to the structural similar AES (C16-18, 1EO) Na (CAS 68585-40-0) was applied. The study on the immobilisation of the water flea Daphnia magna was performed under static conditions in accordance with OECD guideline 202 and GLP (Werhahn, 2006). The test organisms were exposed for 48 hours to a series of eight test item concentrations (1, 2, 4, 8, 16, 32, 64 and 128 mg/L test item;corresponding to 85% a.i.). The test substance concentrations were determined with Methylene Blue Active Substance (MBAS) method for anionic surface active substances. Based on the limit of detection the test item concentration could only be determined with sufficient reliability for the higher test concentrations (>= 8 mg/L). The retrieval rate of the test item was between 73% and 112%. There was no relevant loss of the substance within the 48 hours test duration. The test item was found to induce swimming inability to the exposed organisms. Based on immobilisation the EC50 (48h) for Daphnia magna was 1.4 mg/L a.i. (nominal).
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