Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Classification of p-nonyl phenol for effects in the environment

In determining the classification appropriate to p-nonyl phenol, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below. 




Reliable studies are available to demonstrate that p-nonyl phenol is not persistent in the water and soil compartment thought it is persistent in sediment. Moverover, the chemical is not readily biodegradable in nature and we consider the chemical to be persistent to environment. 


p- nonyl phenol is classified as a persistent (P) chemical. 


Potential to accumulate

The estimated log Kow values for p-nonyl phenol is less than 4 (Log Kow = 3.97). The potential for p-nonyl phenol to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 2000.  


The estimated BCF of p-nonylphenol is highest 103.7 L/kg w/w and below the threshold of 2000. 


Thus, p-nonylphenol does not satisfy the criterion for classification as bio-accumulative (B).


The toxicity values of fish, invertebrates and algae are LC50 = 0.73 mg/L, EC50 = 2.1 mg/L and EC50 = 1.2 mg/L, respectively. These values of fish, invertebrate and algae suggest that classification for aquatic toxicity will be applicable in aquatic medium in acute category 1. Further, the chemical is not readily biodegradable nature and based on the chronic studies the classification of chronic category 1 has also been considered of this substance.


Thus, in summary, p-nonylphenol isclassified as toxic (T) in acute category 1 and chronic category 1.


However, in accordance with Annex XIII of the REACH regulation, p-nonylphenol does not satisfy all the 3 mentioned criteria of P, B and T and so is not a PBT (including vPvB) substance.