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EC number: 230-072-0 | CAS number: 6938-94-9
Endpoint summary
Administrative data
Description of key information
Biodegradation in water:
Estimation Programs Interface Suite (EPI suite, 2018) was run to predict the biodegradation potential of the test chemical in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical is expected to be readily biodegradable.
Biodegradation in water and sediments:
Estimation Programs Interface (EPI Suite, 2018) prediction model was run to predict the half-life in water and sediment for the test chemical. If released in to the environment, 28.3 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.137 %), indicates that test chemical is not persistent in sediment.
Biodegradation in soil:
The half-life period of test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2018). If released into the environment, 69.7 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low .
Additional information
Biodegradation in water:
Various studies have been reviewed for test chemical and its read across chemical for biodegradation endpoint and their results are summarized below.
The objective of the study was to measure Biochemical Oxygen Demand of test chemical over a 5-day period by closed bottle test and thereby calculating percentage degradation on the basis of its theoretical oxygen demand (ThOD). The test contained a control group, a reference group, and a test substance group. The solution of the test substance having a concentration of 2 mg/L in mineral medium, was inoculated with a 0.5 ml/L of surface water (used as inoculum) and kept in completely full closed bottles in BOD incubator at constant temperature of 20 ± 2°C. DO determination on the 0thand 5thday of the experiment was done using Winkler Azide Titration method. The amount of oxygen taken up by the microbial population during biodegradation of the test substance was corrected for uptake by the blank inoculum and BOD5was calculated accordingly. The biochemical degradation of the test substance is expressed as a percentage of ThOD. ThOD, BOD5and % Degradation of the test substance was determined to be 41.27% in 5 days. Thus based on these results it can be concluded that test chemical is readily biodegradable.
In next study the Estimation Programs Interface Suite (EPI suite, 2018) was run to predict the biodegradation potential of the test chemical in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical is expected to be readily biodegradable.
Another study was reviewed from authoritative database ( J check) in this study the Biodegradation experiment was carried out of test chemical by taking activated sludge as inoculums at 30 mg/L concentration for 14 days. Biodegradation was analyzed by using three parameters that are BOD and test material analysis by GC .The initial concentration of test chemical was 100 mg/L. After 2 weeks of incubation percent biodegradation of test chemical was observed to be 83 % by BOD (O2 consumption) parameter, 92 % by TOC removal parameters and 100 % by test material analysis by GC parameter in 14 days. By considering % degradation values it is concluded that test chemical is readily biodegradable.
Last study was also reviewed from J check in this the Biodegradation experiment was performed for test chemical by taking activated sludge as inoculums at 30 mg/L concentration for 14 days. Biodegradation was analyzed by using two parameters that are BOD and test material analysis by GC. The initial concentration of test chemical was 100 mg/L. After 2 weeks of incubation Percent biodegradation of test chemical was observed to be 90% by BOD (O2 consumption) parameter and 100 % by test material analysis by GC parameter in 14 days. On the basis of percent degradation values it is concluded that test chemical is readily biodegradable.
By considering results of all the studies mentioned above it can be concluded that test chemical is readily biodegradable.
Biodegradation in water and sediments:
Estimation Programs Interface (EPI Suite, 2018) prediction model was run to predict the half-life in water and sediment for the test chemical. If released in to the environment, 28.3 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.137 %), indicates that test chemical is not persistent in sediment.
Biodegradation in soil:
The half-life period of test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2018). If released into the environment, 69.7 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low .
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