Registration Dossier
Registration Dossier
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EC number: 415-430-8 | CAS number: 86403-32-9 CYASORB UV-3853 LIGHT STABILIZER; DASTIB 845; SANDUVOR 845
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Due to the insolubility of the substance, acute toxicity testing in algae is difficult to undertake. The EC50 is greater than 495 microgram/L (nominal concentration).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 495 µg/L
- EC10 or NOEC for freshwater algae:
- 495 µg/L
Additional information
An ecotoxicology expert reviewed the OECD 201/EU C.3 acute aquatic toxicity study in algae for the substance Cyasorb (EC 415-430-5) by Ing and Kroon, 2000. He concluded that data on water solubility, previously estimated to be 0.5 mg/L, was generated by an inappropriate method. Concentrations assumed to be dissolved in water were the result of mechanical dislocation from a glass surface. The solubility of the substance is at least 3 orders of magnitude lower than 0.5 mg/L. Furthermore, effects of the substance on algal growth were more likely due to physicochemical interactions of dispersed crystals of the substance, rather than to a standard “toxic” effect. This expert felt that testing according to OECD 201 guidelines is unsuitable for assessing aquatic toxicity of this substance; however, a subsequent test was undertaken (Mayer and Oldesma, 2000) with the finding of no adverse effects on growth by a filtered test material solution at nominal concentrations of 495 microgram/L (although no modification of concentration was made after demonstrated removal of significant particulate material). The amount of this substance estimated to be released into the environment is negligible (See Sections 9 and 10 of the Chemical Safety Report). The ecotoxicology expert further predicted that if the substance were to find its way into the environment, it would more likely bind to particular matter in water, due to its hydrophobic nature, and any physicochemical effect would be unlikely to occur. Thus, the risk of adverse effects to aquatic organisms is below the level of concern.
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