Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 617-298-9 | CAS number: 82097-50-5
Endpoint summary
Administrative data
Description of key information
Two bioaccumulation studies on fish following standard test guidelines and complying with GLP are available and included (Fackler 1991 & Fackler 1992). Low BCF values (1.2 and 1.3, respectively) demonstrate low bioaccumulation potential of the substance, which is supported by the low log Pow values measured for the substance in reliable and valid studies.
Additional information
Low log Pow values <3 over a range of pH values were observed in a valid GLP study according to OECD TG 107 (Burkhard 1994), indicating a low bioaccumulation potential of the substance.
For the bioaccumulation endpoint, two in-vivo bioaccumulation studies are available (Fackler 1991 & Fackler 1992). Both available studies followed standard test guidelines and complied with GLP (Reliability 1). In the first study (Fackler 1991), bluegill sunfish (Lepomis macrochirus) were exposed to the 14C-phenyl-ring-labelled test substance at nominal concentrations of 1.4 – 1.5 mg/L for 28 days uptake phase and 14 days depuration. The bioconcentration factor (BCF) were calculated to be 1.2 in whole fish (bluegill sunfish; steady-state by day 1) at exposure conc. of 1.4 - 1.5 mg/L. No normalization for the lipid content was performed. In the second study (Fackler 1992), bluegill sunfish (Lepomis macrochirus) were exposed to the 14C-triazine-ring- and 14C-phenyl-labelled test substance at nominal concentrations of 1.4 – 1.5 mg/L for 28 days uptake phase and 14 days depuration (35 fish). The test conditions were as following: pH 6.8 – 7.3, 16.9 – 17.1 °C, 16 hours light -8 hours darkness cycle. The water conditions were 30 - 35 mg/L total hardness (as CaCO3) and 0.3 – 1.9 mg/L TOC. The steady state bioconcentration factors of 0.46 for edible tissue and 2.6 for non-edible tissue were determined. This corresponds to whole body bioconcentration factor (BCF) of 1.3. No normalization for the lipid content was performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
