Registration Dossier
Registration Dossier
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EC number: 223-228-4 | CAS number: 3775-90-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96h-LC50 of 2-tert-butylaminoethyl methacrylate to Danio rerio was established to >500mg/L in a OECD gudieline 203 test under GLP conditions (reliability 2).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 500 mg/L
Additional information
The acute toxicity of 2-tert-butylaminoethyl methacrylate was assessed by exposing the fish species Danio rerio in accordance to OECD guideline 203 and GLP. Analytical measurement was performed and measured concentrations was within 80 -120% of the nominal values. The analyses quantification was based on tertiobutyl amino ethanol and not on the parent compound. The test concentrations were: 0, 100, 200 and 500 mg/L (nominal concentrations). After 96 hour of static exposure, 20 % mortality was observed in the highest dose (500 mg/L). In the highest dose, at the end of the test, fish also showed colorations signs. The LC50 value as calculated by Probits method was established to >500 mg/L at 96 h.
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