Registration Dossier
Registration Dossier
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EC number: 223-228-4 | CAS number: 3775-90-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 73.3 mg/L
- EC10 or NOEC for freshwater algae:
- 73.3 mg/L
Additional information
Two studies on toxicity to aquatic algae and cyanobacteria is submitted with this dossier.One of the studies is performed on the 2 -tert butylaminoethyl methacrylated while the other is performed on the read across substance 2-Dimethylaminoethyl methacrylate.
The effect of 2-tert-butylaminoethyl methacrylate on the growth of Pseudokirchneriella subcapitata was evaluted according to an OECD 201 test. At the highest test concentration of 73.30 mg/L (geometric mean of concentrations measured at the beginning and the end of the test), no effect was observed after 72 hours. The ErC50 and NOEC are thus higher than 73.30 mg/L.
For the second study, performed on the read across substance 2-Dimethylaminoethyl methacrylate the original report is not available. However, the report is cited in a per-reviewed OECD SIDS. Hence, the reliability was taken from the OECD report. The ErC50 was established to 69.7 mg/L and the NOEC to 32 mg/L
Reported key values for the chemical safety assessment were taken from the study performed on the actual substance 2 -tert-butylaminoethyl methacrylate and not from the reports on the read across substance 2-Dimethylaminoethyl methacrylate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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