Bis[C5-(linear and branched)-alkyl] benzene-1,4-dicarboxylate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014-02-18 to 2014-06-30

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other:

Version / remarks:

The test was performed based on the following documents:
• European Chemicals Agency (ECHA), Guidance on information requirements and chemical safety assessment, chapter R. 7 A- endpoint specific guidance, May 2008.
• Letinski, D.J. et al. (2002), Slow-stir water solubility measurements of selected alcohols and
diesters, Chemosphere 48, 257-265.
• Standard operating procedures (Standardarbeitsanweisungen, SAA) AN-SOP 903
• Equipment calibration procedures (Geratearbeitsanweisungen, GAA) AN-GAA 1445

Principles of method if other than guideline:

The test was performed based on the following documents:
• European Chemicals Agency (ECHA), Guidance on information requirements and chemical safety assessment, chapter R. 7 A- endpoint specific guidance, May 2008.
• Letinski, D.J. et al. (2002), Slow-stir water solubility measurements of selected alcohols and
diesters, Chemosphere 48, 257-265.
• Standard operating procedures (Standardarbeitsanweisungen, SAA) AN-SOP 903
• Equipment calibration procedures (Geratearbeitsanweisungen, GAA) AN-GAA 1445

GLP compliance:

yes (incl. QA statement)

Type of method:

other: slow-stir method

Key result

Water solubility:

79 µg/L

Conc. based on:

test mat.

Loading of aqueous phase:

10 other: mg/L, second test batch with 25 mg/L

Incubation duration:

> 144 - < 312 h

Temp.:

25 °C

pH:

> 7.2 - < 8.3

	Test batches
	0 mg/L (blank)					10 mg/L				25 mg/L
Stir· ring time [h]	Analyzed test item concentration [µg/L]			Mean value [µg/L]	pH	Analyzed test item concentration [µg/L]		Mean value [µg/L]	pH	Analyzed test item concentration [µg/L]		Mean value [µg/L]	pH
24	0			-	7,2	43		42	7,8	29		28	7,2
	0					41				26
48	0			-	8,0	64		60	7,2	42		41	7,6
	0					56				40
72	0			-	8,2	64		67	7,8	65		65	7,6
	0					70				64
144	0			-	8,1	81		78	8,0	81		79	7,7
	0					74				76
192	0 0			-	8,3	79		74	7,3	81		80	7,7
						68				79
312	0			-	8,0	87		85	7,6	77		77	8,3
	0    ...					83				77

Conclusions:

Water solubility (at room temperature): 79 µg/L

Executive summary:

The water solubility of the test item was determined according to the slow-stir method as described in the following documents:

• European Chemicals Agency (ECHA), Guidance on information requirements and chemical safety assessment, chapter R. 7 A- endpoint specific guidance, May 2008.

• Letinski, D.J. et al. (2002), Slow-stir water solubility measurements of selected alcohols and diesters, Chemosphere 48, 257-265.

Description of key information

Water solubility (at room temperature): 79 µg/L

Key value for chemical safety assessment

Water solubility:

79 µg/L

at the temperature of:

25 °C