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EC number: 214-946-9 | CAS number: 1222-05-5
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Endpoint summary
Administrative data
Description of key information
Four key studies are available for 3 trophic levels:
Plants, EC10 is 7.36 mg/kg soil with 0.66% organic carbon (Corg) or 1.12 organic matter (Morg);
Earthworm and Folsomia NOECs are 45 mg/kg dw soil with 10% Morg or 6% Corg);
Nitrification by micro-organism EC10/NOEC is 1000 mg/kg soil with 0.92% Corg or 1.6% Morg.
Conversion to standard OC: According to ECHA guidance R.10, page 38 the results need to be converted to a standard soil with organic matter (Morg) of 3.4% or 2% organic carbon (Corg) (for the conversion Morg to Corg, Morg is divided by 1.7, Echa guidance Table R.16-8).
The converted results for plants, earthworms, Folsomia and nitrification by micro-organism are: 23, 15,15 and 3696 mg/kg dw soil, respectively. The lowest EC10/NOEC value is the 15 mg/kg dw soil for earthworm and Folsomia, which will be used for the PNEC derivation.
Additional information
In the table below and overview of terrestrial key toxicity studies is presented, without conversion to standard OC
Test species | Guidelines | Results (mg/kg dwt) | Remarks |
Eisenia fetida | ISO11268-2, similar to OECD TG 222 | 4wk-NOEC survival >= 250; 4wk-NOEC growth = 105; 8wk-NOEC (reprod., survival) = 45; Based on nominal concentrations | Key study, K2. Gossmann 1997 artificial soil, 10% sphagnum DIN1
|
Folsomia candida | ISO 11267
| 4wk-NOECreproduction and survival = 45; 4wk-LOEC = 105. Based on nominal concentrations | Key study, K2. Klepka 1997 artificial soil, 10% sphagnum DIN1
|
Brassica napus, Glycine max, Solanum lycopersicum, Cucumis sativus, Avena sativa, Allium cepa | OECD TG 208 | Average EC10growth = 7.63, Based on nominal concentrations | Key study, K1. Spatz & Kowalczyk, 2019 LUFA sandy loam soil Corg: 0.66 ± 0.07% |
Soil microorganisms | OECD TG 216 | 28d-NOECnitrification >= 1000 based on nominal concentrations | Key study, K1. Hammesfahry, 2019 LUFA sandy loam soil; Corg 0.92% |
For 5 plants EC10 values could be derived: 3.55, 5.20, 6.78, 10.3, 12.3. One plant had a NOEC of >1000 mg/kg soil dw and was not included in calculation of the average. The average EC10 was therefore 7.63 mg/kg soil.
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