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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This GLP-compliant study was performed according to OECD Guideline 105.
according to guideline
OECD Guideline 105 (Water Solubility)
Two deviations were reported: 1) change of glassware; 2) in-house water purification system differed from what was outlined in the protocol; neither deviation was considered to have had an impact on the study.
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
1.71 g/L
20 °C
Interpretation of results: soluble (1000-10000 mg/L)
The water solubility of Anisole was determined to be 1.71g/L at 20 degrees C at a pH of 7.

Description of key information

Anisole is soluble in water with solubility of 1.71 g/L at 20°C and pH 7 (experimental result).

Key value for chemical safety assessment

Water solubility:
1.71 g/L
at the temperature of:
20 °C

Additional information

Only one experimental study was available and was selected as key study. The water solubility was determined at 1.71 g/L at 20°C and pH 7.

Anisole is considered as soluble in water.