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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This GLP-compliant study was performed according to OECD Guideline 105.
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
Two deviations were reported: 1) change of glassware; 2) in-house water purification system differed from what was outlined in the protocol; neither deviation was considered to have had an impact on the study.
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
1.71 g/L
Temp.:
20 °C
pH:
7
Conclusions:
Interpretation of results: soluble (1000-10000 mg/L)
The water solubility of Anisole was determined to be 1.71g/L at 20 degrees C at a pH of 7.

Description of key information

Anisole is soluble in water with solubility of 1.71 g/L at 20°C and pH 7 (experimental result).

Key value for chemical safety assessment

Water solubility:
1.71 g/L
at the temperature of:
20 °C

Additional information

Only one experimental study was available and was selected as key study. The water solubility was determined at 1.71 g/L at 20°C and pH 7.

Anisole is considered as soluble in water.