Anisole

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

Beilstein organic substance records contain the critically reviewed and evaluated documents from the Beilstein Handbook of Chemistry as well as data from 176 leading journals in organic chemistry covering the period 1779 to present. An exhaustive list of values and primary references are provided.

GLP compliance:

not specified

Type of method:

other: not specified

Temp.:

25 °C

Vapour pressure:

4.68 hPa

Remarks on result:

other: = 3.51 mm Hg

Temp.:

70 °C

Vapour pressure:

53.062 hPa

Remarks on result:

other: =39.8 mm Hg

Conclusions:

The Beilstein database identifies the vapor pressure of Anisole as 4.68 hPa at 25°C and 53.062 hPa at 70°C.

Reference 2

Endpoint:

vapour pressure

Type of information:

(Q)SAR

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Scientifically acceptable method of estimation.

Principles of method if other than guideline:

MPBPWIN estimates vapor pressure by three separate methods: (1) the Antoine method, (2) the modified Grain method, and (3) the Mackay method. All three calculations assumed a boiling point of 153.70 degrees C from the experimental database to estimate vapor pressure. These experimental values are taken from SRC's PHYSPROP Database.

GLP compliance:

not specified

Type of method:

other: The Antoine method, the modified Grain method, and the Mackay method.

Temp.:

25 °C

Vapour pressure:

489 Pa

Remarks on result:

other: Antoine Method

Temp.:

25 °C

Vapour pressure:

411 Pa

Remarks on result:

other: Modified Grain Method

Temp.:

25 °C

Vapour pressure:

603 Pa

Remarks on result:

other: Mackay Method

Temp.:

25 °C

Vapour pressure:

450 Pa

Remarks on result:

other: Selected VP: Mean of Antoine & Grain methods.

Conclusions:

MPBPWIN estimated vapor pressure at 25 degrees C by three separate methods: the Antoine method, the modified Grain method, and the Mackay method. All three calculations used a boiling point of 153.70 degrees C from the SRC's PHYSPROP Database. The calculated vapor pressures were 489 Pa, 411 Pa, and 603 Pa, respectively. EPI Suite 4.0 selecected 450 Pa as the vapor pressure based on the mean of Antoine & Grain methods.

Reference 3

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

HSDB is a toxicology data file on the National Library of Medicine's (NLM) Toxicology Data Network (TOXNET). All data are referenced and derived from a core set of books, government documents, technical reports and selected primary journal literature. HSDB is peer-reviewed by the Scientific Review Panel (SRP), a committee of experts in the major subject areas within the data bank's scope.

GLP compliance:

not specified

Type of method:

other: not specified

Temp.:

25 °C

Vapour pressure:

3.54 mm Hg

Conclusions:

The Hazardous Substances Data Bank identifies the vapor pressure for Anisole as 3.54 mm Hg at 25 degrees C.

Description of key information

Several peer-reviewed sources indicate the vapour pressure of Anisole at 25 degrees C to be in the range of 3.51 to 3.54 millimeters Mercury (468 - 472 Pa).

Key value for chemical safety assessment

Vapour pressure:

470 Pa

at the temperature of:

25 °C

Additional information

Two available peer-reviewed vapour pressure values at 25 degrees C (468 and 472 Pa) are supported by one peer reviewed vapour pressure value at 70 degrees C and by a calculated values (EPI Suite 4.0). The EPI Suite calculated vapor pressures were 489 Pa, 411 Pa, and 603 Pa using the Antoine method, the modified Grain method, and the Mackay method respectively. EPI Suite 4.0 selected 450 Pa as the vapor pressure based on the mean of Antoine & Grain methods. Based on the average of the two peer reviewed sources the vapour pressure of Anisole is 470 Pa at 25 degrees C.