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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Review of the different end-points of Anisole toxicity (secondary source). The initial reference is not published.

Data source

Reference
Reference Type:
secondary source
Title:
Anisole
Year:
1979
Bibliographic source:
RIFM Monograph: 733 (published 1979: FCT, v17, p243)

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Anisole
EC Number:
202-876-1
EC Name:
Anisole
Cas Number:
100-66-3
Molecular formula:
C7H8O
IUPAC Name:
anisole

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Executive summary:

A dermal LD50 study was conducted in which 5000 mg/kg of Anisole was applied to the skin of 10 rabbits. The animals were observed for mortality and/or systemic effects for 14 days. No further details were provided.

Acute dermal LD50/rabbits > 5000 mg/kg bw was determined.