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EC number: 202-876-1 | CAS number: 100-66-3
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26-04-2010 to 01-07-2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The GLP study was performed according to OECD Test Guideline 117, with no reported or observed deviations.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes
- Remarks:
- OECD GLP
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- Pow
- Partition coefficient:
- 415
- Temp.:
- 30 °C
- Remarks on result:
- other: The pH of the test solution was not reported but the pH of the buffer solution used was 6.09
- Type:
- log Pow
- Partition coefficient:
- 2.62
- Temp.:
- 30 °C
- Remarks on result:
- other: The pH of the test solution was not reported but the pH of the buffer solution used was 6.09
- Conclusions:
- The logarithm of the partition coefficient (log Kow) for Anisole was determined to be 2.62 at 30 degrees C.
Reference
Description of key information
Several peer-reviewed sources indicate the logarithm of the octanol-water partition coefficient of Anisole is 2.11. A K1 study conducted on 97.06% pure anisole showed a log Kow of 2.62.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.62
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