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EC number: 601-722-4 | CAS number: 120570-77-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
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- Flash point
- Auto flammability
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- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
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- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
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- Nanomaterial aspect ratio / shape
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- Nanomaterial surface chemistry
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- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Acute tests evaluating the toxicity of diethyleneglycol diformate (CAS 120570-77-6) to aquatic organisms from three different trophic levels are available. Since the substance is susceptible to abiotic hydrolysis (DT50: 1.24 d (pH7) and 2.98 h (pH8) (HYDROWIN v2.00)) it is likely that the possible effects of the parent substance as well as the hydrolysis productswere assessed in the available studies. Aquatic invertebrates turned out to be the most sensitive taxonomic group with a LC50 (48 h) of 33.1 mg/L, whereas no toxicity was observed in marine fish up to a concentration of 33.1 mg/L after 96 h (nominal). An EC50 (72 h) of 207.8 mg/L was reported for marine algae. Long-term toxicity testing was not deemed necessary.The environmental exposure assessment for diethyleneglycol diformate according to Annex XI, Section 3 indicates no risk for the aquatic compartment (all RCR < 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information). Thus, long-term testing with aquatic invertebrates and fish is not deemed necessary.
Diethyleneglycol diformate caused inhibition of the respiration rate of activated sludge microorganisms resulting in an EC10 (3 h) of 580 mg/L. Nevertheless, the overall potential to cause inhibition of activated sludge microorganisms is low and significant inhibition of the subsequent degradation process in sewage treatment plants is not expected.
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