Registration Dossier
Registration Dossier
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EC number: 601-722-4 | CAS number: 120570-77-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable: 61.1% - 64.3% (O2 consumption) in 28 days (OECD 306)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
One experimental study is available investigating the ready biodegradability of diethyleneglycol diformate (CAS 120570-77-6).
The study was performed with natural seawater as inoculum according to OECD 306 under GLP conditions (Rowlands, 2008). A percental degradation of 61.1% - 64.3% was observed after 28 d. Biodegradation in seawater is generally slower than that in tests with freshwater and activated sludge as inoculum. In this study it is indicated by a long lag-phase of approximately 14 d with a degradation of 2.9% at maximum. According to the “Guidance on information requirements and chemical safety assessment / Chapter R.7b: Endpoint specific guidance” published by ECHA (2012) a removal of > 60% after 28 d in a study according to OECD 306 can be used as evidence that the substance is expected to fulfil the requirements for readily biodegradability.
QSAR calculations using BIOWIN v4.10 support this result (Müller, 2011). The final prediction of the model is that the substance is readily biodegradable. Taking both reliable studies into account, the substance is considered to be readily biodegradable according to the OECD criteria.
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