Registration Dossier
Registration Dossier
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EC number: 208-857-4 | CAS number: 544-01-4
Endpoint summary
Administrative data
Description of key information
Additional information
For diisopentyl ether the base set data are available, including a respiration inhibition study with activated sludge.
One reliable guideline study for short-term toxicity is available for freshwater fish. The critical acute effect concentration for diisopentyl ether is a 96-h LC50 value of 6.82 mg/L (95% CI 4.76 to 9.78 mg/L) in medaka (Oryzias latipes) (Unpublished data, Ministery of Environment Japan, 2005a). This value will be used in the assessment.
For invertebrates short-term toxicity a guideline study is available for Daphnia magna. The critical effect concentration for diisopentyl ether is a 48-h EC50 value of 2.31 mg/L (95% CI 2.02 to 2.67 mg/L) in Daphnia magna (Unpublished data, Ministery of Environment Japan, 2005b). This value will be used in the assessment.
For freshwater algae a guideline study is available for Pseudokirchneriella subcapitata. The critical effect concentrations for diisopentyl ether are a 72-h EC50 value of > 4.36 mg/L and a 72-h NOEC of 1.15 mg/L (Unpublished data, Ministery of Environment Japan, 2005c). These values will be used in the assessment.
Note: A concentration of 4.36 mg/L was the maximum possible concentration of the test solution preparation (20 mg/L, average of measurement value: 4.36 mg/L).
Long-term studies with fish and invertebrates are not available.
For the toxicity of microorganisms a respiration inhibition guideline study with domestic activated sludge is available. The critical effect concentration for diisopentyl ether is a 3-h EC50 value of >19 mg/L (LAUS GmbH, 2011), the 3-h NOEC value will be used in the assessment.
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