Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48h-EC50 for Daphnia magna exposed to Pergafast 425 exceeded a geometric mean concentration of 5.5 µg/L, being considered as the maximum solubility of the test item in test medium.
Key value for chemical safety assessment
Additional information
The short-term toxicity of the test item to aquatic invertebrates was studies in a daphnia acute study according to OECD guideline No. 202. In addition, procedures were based on the test methods described in the OECD series on testing and assessment number 23. Daphnids were exposed to solutions containing 0.10, 1.0, 10 and 100% of the SS, prepared at a loading rate of 100 mg/L. Samples taken from the highest test concentration (i.e. undiluted SS) and the control were analysed. The measured concentrations in the SS were 5.8 µg/L at the start of the test and 5.2 µg/L at the end of the exposure period. Based on the results, the geometric mean concentration was calculated to be 5.5 µg/L in the SS and was used to express effect parameters. No immobility or other effects were observed in the control and at any of the test concentrations throughout the exposure period. In conclusion, the 48h-EC50 for Daphnia magna exposed to Pergafast 425 exceeded a geometric mean concentration of 5.5 µg/L, being considered as the maximum solubility of the test item in test medium. The study is considered to be reliable without restrictions.
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