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Diss Factsheets
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EC number: 223-228-4 | CAS number: 3775-90-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Type of information:
- experimental study planned
- Study period:
- Study planned after the Hydrolysis study according to OECD TG 111 is completed.
- Justification for type of information:
- These studies will be performed in a tiered approach based on first the Hydrolysis study according to OECD TG 111 (as requested by the Compliance check decision CCH-D-2114612447-51-01/F deadline 19-jan-2026). If based on the hydrolysis test, we can conclude that the substance is not persistent, the need for the biodegradation simulation studies will be reconsidered.
In case a half-life of less than 40 days at 12°C is observed for the parent in the hydrolysis test at pH 7 and the bioaccumulation potential of identified degradation products is concluded to be low (log Kow ≤ 4.5), it is considered justified to conclude that the substance is not a PBT/ vPvB substance and that no further biodegradation simulation testing according to OECD TG 308 or 309 is not required to evaluate the persistency and related PBT/vPvB properties of the substance - Guideline:
- OECD Guideline 309 (Aerobic Mineralisation in Surface Water - Simulation Biodegradation Test)
- Transformation products:
- no
- Endpoint:
- biodegradation in water: sediment simulation testing
- Type of information:
- experimental study planned
- Justification for type of information:
- Biodegradation simulation testing will be performed in a tiered approach. After evaluating the results of the biodegradation in water according to OECD 309, we will decide whether to perform further biodegradation simulation testings according to OECD TG 308.
- Guideline:
- OECD Guideline 308 (Aerobic and Anaerobic Transformation in Aquatic Sediment Systems)
- Transformation products:
- no
Referenceopen allclose all
Description of key information
These studies will be performed in a tiered approach based on first the Hydrolysis study according to OECD TG 111 (as requested by the Compliance check decision CCH-D-2114612447-51-01/F). If based on the hydrolysis test, we can conclude that the substance is not persistent, the need for the biodegradation simulation studies will be reconsidered.
Background
The substance is a monomer, which at this >100 tons level is only imported in polymers from outside EU. The residual monomer level in polymer is <0.01%.
2-tert-butylaminoethyl methacrylate (TBAEMA) is considered to be hydrolytically unstable. Half-lives of 3.3 h, 4.5 days and > 1 year were observed for a structurally strongly related substance N,N-Dimethylaminoethyl Methacrylate (DMAEMA) at resp pH 9 at 25 °C, pH 7 at 25 °C and pH 4 at 50 °C. In contrast with DMAEMA, TBAEMA was found the be only partly biodegradable. One of the two hydrolysis products is quickly biodegraded and the other is most likely not.
Key value for chemical safety assessment
- Half-life in freshwater:
- 4.5 d
- at the temperature of:
- 25 °C
- Half-life in freshwater sediment:
- 4.5 d
- at the temperature of:
- 25 °C
Additional information
2-tert-butylaminoethyl methacrylate (CAS 3775 -90 -4) is a monomer used in the manufacture of acrylic copolymers used as ingredients in personal care and industrial products. Manufacture of the monomer and the polymers containing it, takes place outside the European Community. The 2-tert-butylaminoethyl methacrylate is typically incorporated in the polymer at up to 4% with more than >99.75 % of the monomer bound in the polymer with only <0.25 % of unbound residual monomer. The estimated remaining residual fraction is <0.01% in polymers imported into the EU is therefore <0.2 tons (<200kg).
In addition: 2-tert-butylaminoethyl methacrylate is quickly (bio)degraded into two products from which one is quickly further biodegraded to CO2, NH3 and H2O. The other product is unlikely to be further biodegraded.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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