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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19 Jan - 23 Mar 1993
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
84/449
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
340 g/L
Conc. based on:
test mat.
Incubation duration:
4 d
Temp.:
20 °C
pH:
11.1
Remarks on result:
other: Results after 3 and 4 days of incubation were not different, thus, the mean value refers to 8 measurements from 4 experiments over 3 and 4 days.

Validity criteria for the measurement of the water solubility:















Target condition according to guideline:Actual condition according to the study:Validity criteria met:
The individual results from each of the three flasks, which should not differ by more than 15%, are averaged.

Individual results from four flasks did not differ by more than 14%.


yes
Conclusions:
The water solubility of the test substance is 340 g/L (+/- 16.3 g/L) at 20 °C.
Executive summary:

The study was conducted to assess the water solubility. The study was conducted in accordance with EEC Method for "determination of the water solubility", Directive 84/449/EEC, method A.6. The water solubility of the test substance is 340 g/L (+/- 16.3 g/L) at 20 °C.

Description of key information

The study was conducted to assess the water solubility. The study was conducted in accordance with EEC Method for "determination of the water solubility", Directive 84/449/EEC, method A.6. The water solubility of the test substance is 340 g/L (+/- 16.3 g/L) at 20 °C.

Key value for chemical safety assessment

Water solubility:
340 g/L
at the temperature of:
20 °C

Additional information