Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 692-759-5 | CAS number: 1040916-84-4
Endpoint summary
Administrative data
Description of key information
Acute oral: LD50(rat): > 2000 mg/kg bw
Key value for chemical safety assessment
Additional information
In an acute oral toxicity study performed according to the Acute Toxic Class method, 2000 mg/kg bw of the undiluted test item EEIM Acetate were administered to two test groups of three fasted Wistar rats by gavage.
The following test substance-related clinical observations were recorded:
2000 mg/kg (first test group): No mortality occurred. Impaired general state in two out of three animals. Dyspnoea in two out of three animals. Piloerection in two out of three animals.
2000 mg/kg (second test group): Mortality in one out of three animals. No clinical signs. Macroscopic pathological findings in the animal that died: -Liquid clear content in the stomach; -Enhanced bleeding in the glandular stomach.
The mean body weight of the surviving animals increased within the normal range throughout the study period. There were no macroscopic pathological findings in the surviving animals sacrificed at the end of the observation period. The acute oral LD50 was calculated to be LD50, oral, rat > 2000 mg/kg bw.
Justification for classification or non-classification
Based on the results, the test item is no subject to classification and labelling according to Regulation (EC) No 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
