(8α,9R,8'''α,9'''R)-1,1'-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis(6'-methoxycinchonan-1-ium-9-ol) dibromide

Explosiveness

Link to relevant study record(s)

Reference

Endpoint:

explosiveness, other

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Part I: Classification procedures, test methods and criteria relating to explosives of Class 1

Version / remarks:

2015

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: ASTM E573

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Key result

Parameter:

other: Heat of decomposition

Remarks on result:

other: No further testing required, as heat of decomposition was <500 J/g

Remarks:

J/g

The thermogram shows a broad range of exothermic activity from 172 - 382 °C, commencing with two small exothermic peaks. The total normalized energy output from the exothermic region, i.e. the heat of decomposition, is 444 J/g.

Interpretation of results:

GHS criteria not met

Conclusions:

The substance is considered as not explosive as the heat of decomposition determined by Differential Scanning Calorimetry was less than 500 J/g.

Executive summary:

The heat of decomposition of the substance was determined by differential scanning calorimetry under GLP in accordance with the standard ASTM E537. This is a suitable technique for measuring the exothermal decomposition energy as required for screening explosive substances. In accordance with Appendix 6 of the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, a substance can be considered as non-explosive and further testing is not required if the exothermic decomposition energy of a substance is less than 500 J/g. An aliquot of 2.0 mg of the test substance was placed in a high pressure gold-plated stainless steel crucible and heated from 25 to 500 °C at a rate of 5 °C/min. Nitrogen was used as purge gas at a flow rate of 50 to 100 mL/min. The thermogram showed a broad range of exothermic activity from 172 - 382 °C, commencing with two small exothermic peaks. The total normalised energy output from the exothermic peak, i.e. the heat of decomposition, was 444 J/g. This indicated that no further testing on explosive properties was required.

Description of key information

Not explosive, as the heat of decomposition is <500 J/g (GLP, ASTM E537)

Key value for chemical safety assessment

Explosiveness:

non explosive