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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29 July 2016 to 09 September 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- < 0.001 g/L
- Conc. based on:
- other: Total Organic Carbon
- Loading of aqueous phase:
- 0.1 g/L
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- >= 5.9 - <= 6
- Details on results:
- PRELIMINARY TEST
- Preliminary estimates of water solubility at 20.0 ± 0.5 °C are shown in the table below.
DEFINITIVE TEST
- Results of total organic carbon analysis for the definitive test are shown in the table below.
- The concentration (gC/L) of test item in the sample solutions is shown in the table below. - Conclusions:
- Water solubility of the test item was determined to be less than 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L.
- Executive summary:
GUIDELINE
The determination was carried out by the flask method using a procedure designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
RESULTS
Water solubility of the test item was determined to be less than 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L.
Reference
PRELIMINARY ESTIMATES OF WATER SOLUBILITY
Loading rate (g/L) |
Concentration (gTOC/L) for first analysis |
Concentration (gTOC/L) for second analysis |
0.1 |
1.86 x 10-3 |
8.59 x10-4 |
1 |
9.70 x 10-4 |
6.64 x 10-4 |
Blank |
6.12 x 10-4 |
2.43 x 10-4 |
RESULTS OF TOTAL ORGANIC CARBON ANALYSIS IN THE DEFINITIVE TEST
Solution |
TOC (mgTOC/L) |
Matrix blank A |
0.557 |
Matrix blank B |
0.408 |
Sample 1A |
0.558 |
Sample 1B |
0.628 |
Sample 2A |
0.635 |
Sample 2B |
0.694 |
Sample 3A |
0.354 |
Sample 3B |
0.448 |
CONCENTRATION OF TEST ITEM IN THE SAMPLE SOLUTIONS
Sample number |
Concentration (gTOC/L) |
Solution pH |
1 |
5.93 x 10-4 |
6.0 |
2 |
6.65 x 10-4 |
5.9 |
3 |
4.01 x 10-4 |
6.0 |
Description of key information
Water solubility of the test item was determined to be less than 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L (OECD 105 and EU Method A.6).
Key value for chemical safety assessment
- Water solubility:
- 0.001 g/L
- at the temperature of:
- 20 °C
Additional information
GUIDELINE
The determination was carried out by the flask method using a procedure designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
RESULTS
Water solubility of the test item was determined to be less than 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L.
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