Registration Dossier
Registration Dossier
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EC number: 810-288-7 | CAS number: 1700656-13-8
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to fish
The substance was tested for toxicity to fish according to OECD guideline 203 in concentrations of 0/2,2/5/10/22/50/100/220/500/1000 mg/L. Summarizung the individual results the LC50 of the substance can be determined as LC50 > 1000 mg/L.
Long-Term Toxicity to fish
Waiving according to "column 2" in Annex IX of REGULATION (EC) No 1907/2006 (CSA does not indicate need for further investigations)
Short-term toxicity to aquatic invertebrates
Based on the geometric mean measured concentrations of the test item the 48 h-EC50 for Daphnia magna was 475 µg/L (95 % confidence limits: 408 – 545 µg/L). The NOEC after 48 h was 341 µg/L. The LOEC after 48 h was 643 µg/L.
Long-term toxicity to aquatic invertebrates
The effects on reproduction were evaluated based on the reproduction per inserted parent animal, since this parameter is the ecologically most relevant response variable and is required by the OECD test guideline 211 (2012), when a significant trend in mortality is detected.
A summary of the assessed effect levels based on the geometric mean measured concentrations of the test item Antimussol ZJ is given in the table below.
The overall effect threshold for effects of the test item under the test conditions was 28.0 µg/L (NOEC) and 100 µg/L (LOEC) based on the geometric mean measured concentrations of the test item Antimussol ZJ.
Table 1: Endpoints for Reproduction and Mortality (based on the geometric mean measured test item concentrations) Effect values
Antimussol ZJ Geometric mean measured test item concentrations [µg/L]
EC10 Reproduction (with 95% confidence limits) 78.7 (Cl: 38.0 - 162)
EC50 Reproduction (with 95% confidence limits 119 (Cl: 28.6 - 467)
LOEC Reproduction 100
NOEC Reproduction 28.0
LC20 Adult mortality after 21 days (with 95% confidence limits) 104 (Cl: 68.2 - 138)
LC50 Adult mortality after 21 days (with 95% confidence limits) 152 (Cl: 113 - 206)
LC100 Adult mortality after 21 days 303
LOEC Adult mortality after 21 days 303
NOEC Adult mortality after 21 days 100
Toxicity to aquatic algae
In this study the test item was found to inhibit the growth of the freshwater green alga Desmodesmus subspicatus after 72 hours. The NOEC-value of the test item for both inhibition of growth rate and inhibition of yield after 72 hours was 310 µg/L. The EC50-values of the test item for inhibition of growth rate (ErC50) and yield (EyC50) with 95 % Confidence Intervals after 72 hours were 962 (890 – 1046) µg/L and 743 (608 – 1029) µg/L, respectively.
All effect levels are given based on geometric mean measured concentrations of the test item.
Toxicity to microorganisms
The substance sowed no effect on activated sludge up to a test concentration of 1000 mg/L.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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